Btb and cnc
WebSep 1, 2013 · BTB and CNC homology 1 (Bach1) is a transcriptional repressor of antioxidative enzymes, such as heme oxygenase-1 (HO-1). Oxidative stress is reportedly involved in insulin secretion impairment and obesity-associated insulin resistance. However, the role of Bach1 in the development of diabetes is unclear. WebBTB and CNC homology 1 (Bach1) is a member of the Cap ‘n’ Collar and basic region leucine zipper family (CNC-bZip) of transcription factors. It is widely expressed in mammalian tissues, and the human variant consists …
Btb and cnc
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WebJul 18, 2024 · Rosner and colleagues further noted that BTB domain and CNC homolog 1 (BACH1), a transcription factor which suppresses RKIP transcription, was induced by HDAC inhibitor treatment , explaining the lack of RKIP induction by these inhibitors. They also found that the histone methyltransferaseEZH2 (enhancer of zeste 2 polycomb repressive … WebApr 10, 2024 · The BTB and CNC homology 1 (BACH1) target genes are involved in the oxidative stress response and in control of the cell cycle. The BACH1 target genes …
WebJan 3, 2024 · We considered that up-regulation of these genes attenuates ferroptosis induction and found that the transcription factor BTB domain and CNC homolog 1 (BACH1), a regulator in heme and iron metabolism, promotes ferroptosis by repressing the transcription of a subset of the erastin-induced protective genes. WebAntigen: BTB and CNC homology 1, basic leucine zipper transcription factor 2 Available to For-Profits: Yes Antigen Species: Human Hybridoma Cells Available (Non-Profit): Yes Isotype: MIgG2a Depositor: Common Fund – Protein Capture Reagents Program Host Species: mouse Antigen Sequence: Positive Tested Species Reactivity: Human
WebBTB and CNC homology 1 (Bach1) is a heme-responsive transcription factor that normally represses HO-1 expression. In this study, we evaluated the changes in HO-1, ALAS1, … WebJan 28, 2024 · BTB domain and CNC homology 1 (BACH1) is a transcription factor that is highly expressed in tumors including breast and lung, relative to their non-tumor tissues. BACH1 is known to regulate multiple physiological processes including heme homeostasis, oxidative stress response, senescence, cell cycle, and mitosis. In a tumor, BACH1 …
WebNov 5, 2024 · Heme also functions as an intracellular activator of antioxidant and globin gene expression. Heme binds to the transcriptional repressor BTB and CNC homolog 1 (BACH1), which relieves BACH1's repression of gene transcription.
WebCatalog Number MK202717. Quantity 1 kit. Type qPCR Template Standards. Target Bach1. Species Mouse. NCBI Full Gene Name BTB and CNC homology 1, basic leucine zipper transcription factor 1. NCBI Gene Aliases 6230421P05Rik, AI323795. ari 34+35WebBoth pathways might involve the regulation of BTB and CNC homology 1 (BACH1), which is the repressor transcription regulator factor of the HO-1 gene. Long-term continuous efferocytosis of apoptotic thymocytes is not affected by the loss of HO-1, but that of eRBCs is inhibited. This latter is related to an internal signaling pathway that ... balamory dvdWebDec 23, 2024 · The BTB and CNC homology 1 (BACH1) target genes are involved in the oxidative stress response and in control of the cell cycle. J Biol Chem. 2011;286(26):23521–32. Article CAS PubMed PubMed Central Google Scholar Zhou Y, Wu H, Zhao M, Chang C, Lu Q. The Bach family of transcription factors: a comprehensive … ari360WebFeb 17, 2024 · Notably, the transcription factor BTB and CNC homology 1 (Bach1), a key factor in responding to conditions of oxidative stress, is increased in lung cancer after CIH exposure in vitro and in vivo. balamory danceWebConclusions: This finding suggests that heme controls a macrophage iron recycling regulon involving Btb and Cnc Homology 1 and Nuclear Factor Erythroid 2-like to assure the coordinated degradation of heme by heme oxygenase 1, iron storage and detoxification by ferritin, and iron export by iron export protein ferroportin. MeSH terms Animals balamory days out uk dvdWebBTB and CNC homology1 (Bach1) is a regulator of oxidative stress and participates in the pathogenesis of multiple lung diseases. Thus, this study aimed to determine the … balamory days out uk dvd 2004WebMar 19, 2024 · BTB and CNC homology 1 inhibition ameliorates fibrosis and inflammation via blocking ERK pathway in pulmonary fibrosis. Bach1 derepression is neuroprotective … ari 35912