Dysregulation of lipid metabolism
WebMay 26, 2016 · We discuss the mechanisms by which the core molecular clock drives rhythms in lipid biosynthesis and catabolism in different metabolic tissues, as well as the … WebAug 23, 2016 · Lipid metabolism disorders, such as Gaucher disease and Tay-Sachs disease, involve lipids. Lipids are fats or fat-like substances. They include oils, fatty acids, …
Dysregulation of lipid metabolism
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WebIt is difficult to conclude the reason for the differential expression of lipid metabolism genes since plant oils are devoid of cholesterol and LC-HUFA, and contain high amounts of C 18PUFA precursors and phytosterols com- pared to fish oil [15–17]. WebNov 18, 2024 · Reprogramming of lipid metabolism is one of the main features of cancer cells and major factors of tumorigenesis and metastasis [ 10 ]. Strikingly, an increasing number of metabolic pathways including lipid metabolism can ultimately converge on ferroptosis [ 11 ].
Serum concentrations of 483 lipids from COVID-19 patients were processed by multivariate analysis using MetaboAnalyst 4.0 (http://www.metaboanalyst.ca)49,50,51. The lipidic dataset was imputed to remove the missing values, log(2)-transformed and scaled according to … See more A Regione-Campania-cohort of 53 patients with a diagnosis of COVID-19 (SARS-CoV-2 infection) admitted at one of the following hospitals was … See more Serum lipidome content was investigated by mass spectrometry-based targeted metabolomics41,42. The lipidomic platform was set to … See more The serum adiponectin concentrations were measured by enzyme-linked immunosorbent assay (ELISA) as previously reported21. … See more Concentrations of TSLP protein in blood serum were evaluated by enzyme-linked immunosorbent assay (ELISA) (Human TSLP Uncoated ELISA … See more WebAug 30, 2024 · Alterations in lipid metabolism are an important metabolic rewiring phenomenon for malignant cells to maintain their rapid proliferation in the hypoxic …
WebThe primary pathology of NAFLD is the destruction of lipid metabolism homeostasis in the body. 31 Among them, ... differences in the severity of liver injury induced by a choline- …
WebOct 21, 2016 · Hypercaloric diets lead to the dysregulation of multiple lipid metabolic pathways, which contributes to the onset and progression of metabolic disease.
WebInhibition of HIF-2α protein reversed lipid metabolism dysregulation induced by acute hypoxia in HepG2 cells, which suggested that HIF-2α signaling may be relevant to oxygen … tea woodland nestingWebAltogether, research in the field of pulmonary fibrosis continues to suggest that metabolic dysregulation acts as a key contributor to the pathogenesis of the disease, and that drugs targeting different aspects of cellular metabolism, including glycolysis, mitochondrial oxygen consumption, and lipid metabolism, should be strongly considered for ... teawood menuWebThere are three processes of lipid metabolism in macrophages: cholesterol uptake, esterification, and efflux. However, during atherosclerosis, dysregulation of lipid … tea wooden trayWebThree molecules play key roles in the regulation of triglyceride metabolism: apolipoprotein C-III(ApoC-III), angiopoietin-like protein 4(ANGPLT4), and lipoprotein lipase(LPL). The aim of … teawood 茶木WebJul 29, 2024 · Autophagy modulates major pathological changes, including hepatic lipid metabolism, inflammation, and fibrosis, suggesting the potential of modulating autophagy … spanner head cam latchWebWe used bioinformatic analysis and examined changes in lipid metabolism in HCC cells in response to matrix stiffness. Moreover, ACADL was identified as a key enzyme, initiating the FAO process, modulated by matrix stiffness. Lipid metabolic reprogramming influenced by matrix stiffness was interacted in an ACADL-dependent mechanoresponsive manner. tea word traceWebMar 9, 2024 · 1. Introduction. Asthma is characterized by airway hyper-responsiveness, mucus hypersecretion, infiltration of the airway by eosinophils and type 2 (T2) immune … tea wordle