WebFeb 9, 2016 · Detection of Ototoxicity Types of testing. Given the substantial risk of ototoxicity associated with platinum chemotherapy and radiation involving the ear and auditory nerve, prospective auditory evaluations to allow for the early detection of hearing loss are indicated for patients receiving therapy with ototoxic potential. For patients with life-threatening illnesses that warrant treatment with ototoxic drugs, communication ability is a central quality of life issue. Identifying ototoxic damage early can improve treatment outcome by minimizing hearing loss progression, and by counseling and rehabilitation. Initial ototoxic drug exposure … See more The purpose of the program drives many decisions about program implementation. For example, if the purpose is to prevent or minimize spread of ototoxic hearing loss into frequencies important for understanding … See more Ototoxicity is determined by comparing baseline data, ideally obtained prior to ototoxic drug administration, to the results of subsequent monitoring tests. In this way, each patient serves as his or her own control. ASHA’s … See more The chemotherapeutic agents cisplatin and carboplatin, and certain aminoglycoside antibiotics have a high incidence of ototoxic hearing loss. A program might target … See more Two primary resources for patient identification include key medical staff and hospital pharmacy medication lists. Identifying patients … See more
Aminoglycoside-Induced Ototoxicity: Test Before You Treat?
WebFeb 26, 2024 · Ototoxicity monitoring protocol should be supplemented with genetic screening to identify individuals susceptible to ototoxicity. This measure could potentially prevent hearing loss by avoiding administration of ototoxic drugs when identified potential confounders increase the risk of ototoxicity. WebOtotoxicity diagnosis involves the following tests: Audiometric or behavioral hearing tests. These hearing tests check the sounds that you can or can’t hear. Your audiologist will use … knd s01e12
Genetic susceptibility to aminoglycoside ototoxicity - PubMed
WebJun 3, 2024 · Ototoxicity: toxicity (the state of being poisonous or damaging) to the ear. The term ototoxicity is used in medicine to refer to substances, typically medications, which … WebSep 1, 2002 · Genetic testing for susceptibility to aminoglycoside ototoxicity is complicated by the fact that the A1555G mutation carries a risk for hearing loss without exposure to aminoglycoside antibiotics ... WebObjectives: Cisplatin-induced ototoxicity is a common permanent consequence of curative chemoradiation for locally advanced head and neck squamous cell carcinoma (HNSCC). Predictors of ototoxicity in HNSCC were examined. Materials and methods: In this prospective, observational cohort study, 206 adult HNSCC patients underwent … red bird yellow beak