WebI received Ph.D. at Johns Hopkins University where I discovered proteins physically linking RNA polymerase II transcription and RNA processing in eukaryotic cells. During my postdoc at Novartis ... WebMar 21, 2024 · RBM15 (RNA Binding Motif Protein 15) is a Protein Coding gene. Diseases associated with RBM15 include Megakaryoblastic Acute Myeloid Leukemia With …
The Putative RNA-Binding Protein Dri1 Promotes the Loading of …
RNA-binding proteins (often abbreviated as RBPs) are proteins that bind to the double or single stranded RNA in cells and participate in forming ribonucleoprotein complexes. RBPs contain various structural motifs, such as RNA recognition motif (RRM), dsRNA binding domain, zinc finger and others. They are … See more Many RBPs have modular structures and are composed of multiple repeats of just a few specific basic domains that often have limited sequences. These sequences are then arranged in varying combinations to fulfill the need for … See more RNA processing and modification Alternative splicing Alternative splicing is a mechanism by which different forms of mature mRNAs (messengers RNAs) are generated from the same gene. It is a regulatory mechanism by … See more RNA-binding proteins' transcriptional and post-transcriptional regulation of RNA has a role in regulating the patterns of gene expression during development. Extensive research on the nematode C. elegans has identified RNA-binding proteins as essential factors … See more As RNA-binding proteins exert significant control over numerous cellular functions, they have been a popular area of investigation for many researchers. Due to its importance in the … See more As nuclear RNA emerges from RNA polymerase, RNA transcripts are immediately covered with RNA-binding proteins that regulate every aspect of RNA metabolism and function including RNA biogenesis, maturation, transport, cellular localization and … See more RNA-binding proteins exhibit highly specific recognition of their RNA targets by recognizing their sequences, structures, motifs and RNA modifications. Specific binding of the RNA-binding proteins allow them to distinguish their targets and regulate a variety of … See more RBPs are emerging to play a crucial role in tumor development. Hundreds of RBPs are markedly dysregulated across human cancers and showed … See more WebNov 30, 2015 · RNA-binding proteins (RBPs) are involved in various post-transcriptional gene regulatory processes and are also functionally important members of the ribosome and the spliceosome. However, RBPs and their interactions with RNA are less well-studied in comparison to DNA-binding proteins. We have classified the jeanne headley
Nicole Stone - Senior Scientist, RNA and Targeted ... - LinkedIn
WebSeveral proteins, including RNA polymerase participate in the transcription process. Of these, the transcription factor is essential for initiating and regulating the transcription of … WebApr 11, 2024 · where ei and pi represent the i-th physico-chemical property of the amino acids from peptides e and p, and n is equal to the target peptide length. 5. mRNA and peptide tissue specific expression mRNA expression in TPMs (GTEx) 18 and protein expression level (Human Protein Atlas) 19 of the putative OTEs are added in order to … WebTrypanosoma cruzi RNA-binding protein ALBA30 aggregates into cytoplasmic foci under nutritional stress ... jeanne henry pittsburgh pa