WebAlthough SCLC appears morphologically homogeneous, the latest data from murine models and human tumors indicate the existence of SCLC subtypes, classified on differential expression of these transcription factors: ASCL1, NEUROD1, POU2F3, or YAP1 with different therapeutic vulnerabilities ( 6 ). Web17 Feb 2024 · SCLC subtypes were recently defined by neuroendocrine transcription factor (NETF) expression. Circulating-tumor-cell-derived explant models (CDX) recapitulate donor patients’ tumor morphology,...
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Web27 Mar 2015 · The Southern Christian Leadership Conference’s (SCLC) main aim was to advance the cause of civil rights in America but in a non-violent manner. From its inception in 1957, its president was Martin Luther King – a post he held until his murder in 1968. As its title suggests, the input into the SCLC came primarily from the church. Web23 Jan 2024 · SCLC is a single histological category and is characterized by its central location, rapid tumor growth, early metastasis, and association with numerous … laura hume university of dayton
Cancers Free Full-Text Pathology and Classification of SCLC
Webkörper gelten als sichere Tumormarker [7, 16]. Die allgemein schlechte Progno-se steht im Zusammenhang mit irrever- ... Ca Karzinom, SCLC“small cell lung cancer”. Web24 Jan 2024 · Small Cell Lung Cancer (SCLC) tumors are heterogeneous mixtures of transcriptional subtypes. Understanding subtype dynamics could be key to explaining the aggressive properties that make SCLC a recalcitrant cancer. Applying archetype analysis and evolutionary theory to bulk and single-cell transcriptomics, we show that SCLC cells … Web28 Mar 2024 · Tumormarker zur Verlaufskontrolle und Nachsorge (nicht Früherkennung) NSE (kleinzelliges Bronchial-CA, SCLC) CEA ( Adenokarzinom) CYFRA 21-1, SCCA ( Plattenepithelkarzinom) proGRP (SCLC) Immunhistochemie Zur Differenzierung der jeweiligen histologischen Subtypen ist der Nachweis von immunhistochemischen … laura hurt borderline personality disorder